Josephine Wee, Ph.D.

Josephine Wee, Ph.D.

  • Assistant Professor of Food Science
432 Rodney A. Erickson Food Science Building
University Park, PA 16802

Areas of Expertise

  • Food microbiology
  • Food safety
  • Genomics of food-associated fungi (Mycotoxins)
  • Evolutionary biology
  • Toxicology
  • Nutritional immunology

Education

  • Postdoc, Nutritional Immunology and Toxicology, Michigan State University, Michigan
  • Postdoc, Evolutionary Biology, Cornell University, Ithaca, New York
  • Ph.D., Food Science and Environmental Toxicology, Michigan State University, Michigan
  • B.S., Food Science, Michigan State University, Michigan

Research

The goal of our research is to understand the role of fungi (yeast and mold) and their contribution to food safety, quality, and sustainability. We use genomics and molecular biology approaches spanning diverse food and agriculture ecosystems to prevent spoilage and food waste, enhance food quality, and create a sustainable food system. 

Awards and Honors

2014-2015 Liberty Hyde Bailey Scholars Program, Graduate Fellowship Award in Teaching (Michigan State University, USA)

2014 German Excellence Program Recipient, Jena School of Microbial Communication (Hans Knöll Institute, Germany) 

2009 Marshall Plan Foundation Scholarship Recipient (BOKU Vienna, Austria)

2008 Delton and Dianne Parks Scholarship Recipient, Department of Food Science and Human Nutrition (Michigan State University, USA) 

2008 Virginia Dare Undergraduate Award Recipient

Publications

A Digital Fluency Framework to Support 21st-Century Skills
Change: The Magazine of Higher Learning, Fleming, E, Robert, Jenay, Sparrow, Jennifer, Wee, Josephine, Dudas, P, Slattery, M, 2021

Docosahexaenoic Acid Suppresses Silica-Induced Inflammasome Activation and IL-1 Cytokine Release by Interfering With Priming Signal
Frontiers in Immunology, Wierenga, Kathryn A., Wee, Josephine, Gilley, Kristen N., Rajasinghe, Lichchavi D., Bates, Melissa A., Gavrilin, Mikhail A., Holian, Andrij, Pestka, James J., 2019

Novel insights into global translational regulation through Pumilio family RNA-binding protein Puf3p revealed by ribosomal profiling
Current Genetics, Wang, Zhe, Sun, Xuepeng, Wee, Josephine, Guo, Xiaoxian, Gu, Zhenglong, 2019

Understand the genomic diversity and evolution of fungal pathogen Candida glabrata by genome-wide analysis of genetic variations
Methods, Guo, Xiaoxian, Zhang, Ruoyu, Li, Yudong, Wang, Zhe, Ishchuk, Olena P., Ahmad, Khadija M., Wee, Josephine, Piskur, Jure, Shapiro, Joshua A., Gu, Zhenglong, 2019

Activation of aflatoxin biosynthesis alleviates total ROS in Aspergillus parasiticus
Toxins, Kenne, Gabriel J., Gummadidala, Phani M., Omebeyinje, Mayomi H., Mondal, Ananda M., Bett, Dominic K., McFadden, Sandra, Bromfield, Sydney, Banaszek, Nora, Velez-Martinez, Michelle, Mitra, Chandrani, Mikell, Isabelle, Chatterjee, Saurabh, Wee, Josephine, Chanda, Anindya, 2018

The fungal bZIP transcription factor AtfB controls virulence-associated processes in Aspergillus parasiticus
Toxins, Wee, Josephine, Hong, Sung Yong, Roze, Ludmila V., Day, Devin M., Chanda, Anindya, Linz, John E., 2017

Bioactive compounds in Diospyros mafiensis roots inhibit growth, sporulation and aflatoxin production by Aspergillus flavus and Aspergillus parasiticus
World Mycotoxin Journal, Mmongoyo, J. A., Nair, M. G., Linz, J. E., Wu, F., Mugula, J. K., Dissanayake, A. A., Zhang, C., Day, D. M., Wee, Josephine, Strasburg, G. M., 2017

Effects of zinc chelators on aflatoxin production in Aspergillus parasiticus
Toxins, Wee, Josephine, Day, Devin M., Linz, John E., 2016

Aflatoxin biosynthesis is a novel source of reactive oxygen species—a potential redox signal to initiate resistance to oxidative stress?
Toxins, Roze, Ludmila V., Laivenieks, Maris, Hong, Sung Yong, Wee, Josephine, Wong, Shu Shyan, Vanos, Benjamin, Awad, Deena, Ehrlich, Kenneth C., Linz, John E., 2015

Aflatoxin Biosynthesis: Regulation and Subcellular Localization, Linz, John, Wee, Josephine, Roze, Ludmila, 2015

Evidence that a transcription factor regulatory network coordinates oxidative stress response and secondary metabolism in aspergilli
MicrobiologyOpen, Hong, Sung Yong, Roze, Ludmila V., Wee, Josephine, Linz, John E., 2013

Stress-related transcription factor AtfB integrates secondary metabolism with oxidative stress response in aspergilli
Journal of Biological Chemistry, Roze, Ludmila V., Chanda, Anindya, Wee, Josephine, Awad, Deena, Linz, John E., 2011